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Reduction of the Bacterial Genome by Transposon-Mediated Random Deletion
- Source :
- ACS synthetic biology. 11(2)
- Publication Year :
- 2022
-
Abstract
- Genome reduction is an important strategy in synthetic biology for constructing functional chassis cells or minimal genomes. However, the limited knowledge of complex gene functions and interactions makes genome reduction by rational design encounter a bottleneck. Here, we present an iterative and random genome reduction method for
Details
- ISSN :
- 21615063
- Volume :
- 11
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- ACS synthetic biology
- Accession number :
- edsair.doi.dedup.....120085f01011611773ada3251ca96a43