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Naproxen as an alternative to aspirin for the treatment of arthritis of rheumatic fever: a randomized trial
- Source :
- The Journal of Pediatrics. 143:399-401
- Publication Year :
- 2003
- Publisher :
- Elsevier BV, 2003.
-
Abstract
- We performed a prospective, randomized, open-label equivalence study comparing the use of naproxen to aspirin in 33 patients with rheumatic fever. The mean time until resolution of arthritis was 2.9+/-2.9 days in both groups. Liver enzyme elevations were more frequent in the aspirin group (P=.002). We conclude that naproxen is as effective, is easier to use, and is safer than aspirin in the treatment of the arthritis of rheumatic fever.
- Subjects :
- Male
medicine.medical_specialty
Naproxen
Time Factors
Adolescent
Arthritis
Gastroenterology
law.invention
Randomized controlled trial
law
Internal medicine
medicine
Humans
Prospective Studies
Child
Prospective cohort study
Aspirin
medicine.diagnostic_test
business.industry
Anti-Inflammatory Agents, Non-Steroidal
medicine.disease
Surgery
Clinical trial
Treatment Outcome
Therapeutic Equivalency
Child, Preschool
Erythrocyte sedimentation rate
Pediatrics, Perinatology and Child Health
Rheumatic fever
Female
Rheumatic Fever
business
medicine.drug
Subjects
Details
- ISSN :
- 00223476
- Volume :
- 143
- Database :
- OpenAIRE
- Journal :
- The Journal of Pediatrics
- Accession number :
- edsair.doi.dedup.....11e90beb5126bd113235148d0c4e4f22