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Artificial membranes for membrane protein purification, functionality and structure studies
- Source :
- Biochemical Society Transactions. 44:877-882
- Publication Year :
- 2016
- Publisher :
- Portland Press Ltd., 2016.
-
Abstract
- Membrane proteins represent one of the most important targets for pharmaceutical companies. Unfortunately, technical limitations have long been a major hindrance in our understanding of the function and structure of such proteins. Recent years have seen the refinement of classical approaches and the emergence of new technologies that have resulted in a significant step forward in the field of membrane protein research. This review summarizes some of the current techniques used for studying membrane proteins, with overall advantages and drawbacks for each method.
- Subjects :
- 0301 basic medicine
Bacteria
Computer science
Peripheral membrane protein
Eukaryota
Membrane Proteins
Membranes, Artificial
Biological membrane
Biochemistry
03 medical and health sciences
030104 developmental biology
Membrane
Membrane protein
Methods
Humans
Biochemical engineering
Protein–lipid interaction
Integral membrane protein
Function (biology)
Subjects
Details
- ISSN :
- 14708752 and 03005127
- Volume :
- 44
- Database :
- OpenAIRE
- Journal :
- Biochemical Society Transactions
- Accession number :
- edsair.doi.dedup.....11a5345d755f175e0f51ed7326dec789
- Full Text :
- https://doi.org/10.1042/bst20160054