Back to Search
Start Over
Erratum to: Axillary recurrence rate following negative sentinel node biopsy for invasive breast cancer: long-term follow-up
- Source :
- Annals of surgical oncology. 17(2)
- Publication Year :
- 2009
-
Abstract
- Sentinel lymph node (SLN) biopsy has replaced axillary lymph node dissection (ALND) as the staging procedure for breast cancer. SLN biopsy causes less morbidity and is more cost effective than complete ALND. Lymphatic mapping and SLN biopsy have a low false-negative rate, but long-term outcomes in large consecutive series of patients are unavailable.Retrospective review of a prospectively accrued institutional breast cancer database was performed. The initial mapping of 1,528 patients with invasive breast cancer that demonstrated negative sentinel node biopsy and no axillary dissection in 1,530 cases between January 1995 and June 2003 were collated and reviewed to achieve a long-term follow-up. These 1,528 patients were reviewed for follow-up time, local recurrences, distant metastases, and survival.A total of 1,530 consecutively mapped invasive breast cancer cases had negative SLN biopsy and no ALND. The mean invasive tumor size of was 1.40 cm. Of patients, 1,212 (79.2%) underwent lumpectomy and 318 (20.8%) underwent mastectomy. Median follow-up was 63 months (range 0.1-144 months). There have been 4 (0.26%) cases presenting with local axillary recurrences, 54 (3.53%) cases presenting with local recurrences in the ipsilateral breast/chest wall, and 24 (1.57%) cases presenting with distant metastases.These data confirm that SLN biopsy is an effective and safe alternative to ALND for detection of nodal metastases in patients with invasive breast cancer and validates its use as the standard tool for nodal staging.
- Subjects :
- Adult
medicine.medical_specialty
Long term follow up
Breast Neoplasms
Adenocarcinoma
Breast cancer
Surgical oncology
Biopsy
medicine
Humans
Neoplasm Invasiveness
Prospective Studies
Aged
Neoplasm Staging
Retrospective Studies
Aged, 80 and over
medicine.diagnostic_test
business.industry
Sentinel Lymph Node Biopsy
General surgery
Carcinoma, Ductal, Breast
Sentinel node
Middle Aged
medicine.disease
Adenocarcinoma, Mucinous
Survival Rate
Carcinoma, Lobular
Treatment Outcome
Oncology
Lymphatic Metastasis
Axilla
Surgery
Female
Lymph Nodes
Neoplasm Recurrence, Local
business
Follow-Up Studies
Subjects
Details
- ISSN :
- 15344681
- Volume :
- 17
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Annals of surgical oncology
- Accession number :
- edsair.doi.dedup.....119a3bef09fe41fa2eb7c4dfe3f56e20