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Stimulation of ornithine decarboxylase activity by luteinizing hormone releasing hormone in the testis of immature rat
- Source :
- Scopus-Elsevier
- Publication Year :
- 1982
- Publisher :
- Elsevier BV, 1982.
-
Abstract
- The activity of ornithine decarboxylase (ODC) was found to increase in the testis of immature rats following intratesticular injection with luteinizing hormone releasing hormone (LHRH). Maximal stimulation of ODC activity occurred with 1 μg of the hormone at 2 h. The enzyme activity returned to control levels at 4 h. The minimal effective dose was found to be 0.1 μg per testis. The stimulating effect of LHRH was confined to Leydig cells alone. The seminiferous tubules did not show any change in ODC activity following LHRH treatment. These results show that LHRH acts directly on the testis and influences the levels of ODC in the Leydig cells of rat.
- Subjects :
- Male
endocrine system
medicine.medical_specialty
genetic structures
Carboxy-Lyases
Biophysics
Stimulation
Ornithine Decarboxylase
Biochemistry
Ornithine decarboxylase activity
Ornithine decarboxylase
Gonadotropin-Releasing Hormone
Internal medicine
Testis
medicine
Animals
Sexual maturity
Sexual Maturation
Odc activity
Molecular Biology
biology
Chemistry
fungi
Leydig Cells
Rats, Inbred Strains
Cell Biology
Seminiferous Tubules
Enzyme assay
Rats
Kinetics
Endocrinology
biology.protein
Luteinizing hormone
hormones, hormone substitutes, and hormone antagonists
Hormone
Subjects
Details
- ISSN :
- 0006291X
- Volume :
- 109
- Database :
- OpenAIRE
- Journal :
- Biochemical and Biophysical Research Communications
- Accession number :
- edsair.doi.dedup.....118fbd3db4eb79ed4cf1f2f2e3ac41e9