Geographic and intra‐racial disparities in early‐onset colorectal cancer in the SEER 18 registries of the United States

Background Although early‐onset colorectal cancer (EOCRC) incidence rates (IRs) are increasing, geographic and intra‐racial IR disparities are not well defined. Methods 2000‐2015 Surveillance, Epidemiology, and End Results (SEER) program CRC IR Analysis (170,434 cases) was performed from ages 30 to 60 in four US regions, 18 individual registries, metropolitan and nonmetropolitan locations and stratified by race. Analyses were conducted in 1‐year and 5‐year age increments. Results Wide US regional EOCRC IR variations exist: For example, age 45 IRs in the south are 26.8/100,000, 36.0% higher than the West, 19.7/100,000 (p
This analysis of SEER 18 early‐onset colorectal cancer data reveals marked disparities by geography and within racial groups (intra‐racial) across the United States. This data can be used to target public health interventions and guide future studies on etiology.