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Judgement Post-Stratification for Designed Experiments
- Source :
- Biometrics. 64:345-354
- Publication Year :
- 2008
- Publisher :
- Wiley, 2008.
-
Abstract
- In many scientific studies, information that is not easily translated into covariates is ignored in the analysis. However, this type of information may significantly improve inference. In this research, we apply the idea of judgment post-stratification to utilize such information. Specifically, we consider experiments that are conducted under a completely randomized design. Sets of experimental units are formed, and the units in a set are ranked. Estimation is performed conditional on the sets and ranks. We propose a new estimator for a treatment contrast. We improve the new estimator by Rao-Blackwellization. Asymptotic distribution theory and corresponding inferential procedures for both estimators are developed. Simulation studies quantify the superiority of the new estimators and show their desirable properties for small and moderate sample sizes. The impact of the new techniques is illustrated with data from a clinical trial.
- Subjects :
- Statistics and Probability
Analysis of covariance
Biometry
Models, Statistical
General Immunology and Microbiology
Applied Mathematics
Inference
Estimator
Contrast (statistics)
General Medicine
computer.software_genre
General Biochemistry, Genetics and Molecular Biology
Decision Support Techniques
Set (abstract data type)
Research Design
Sample size determination
Data Interpretation, Statistical
Covariate
Computer Simulation
Variance reduction
Data mining
General Agricultural and Biological Sciences
computer
Randomized Controlled Trials as Topic
Mathematics
Subjects
Details
- ISSN :
- 0006341X
- Volume :
- 64
- Database :
- OpenAIRE
- Journal :
- Biometrics
- Accession number :
- edsair.doi.dedup.....11670cc7d3178891edf4185fb16e3af7