Differences in reactivity of four butyrylcholinesterase isozymes towards substrate and inhibitors

Authors :: R.D. O'Brien
Y.C. Chiu
R.K. Tripathi
Source :: Biochemical and biophysical research communications. 46(1)
Publication Year :: 1972
Abstract: Four isozymes of horse serum butyrylcholinesterase have been resolved by means of polyacrylamide gel electrophoresis combined with specific substrate staining and gel-scanning procedures. They differ 5-fold in their Km for butyrylthiocholine and 5 and 7-fold in reactivity with two organophosphates, malaoxon and Tetram.

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