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Impulse-powered needle-free syringe for vaccine/drug injection
- Source :
- Technology and Health Care. 25:1131-1138
- Publication Year :
- 2017
- Publisher :
- IOS Press, 2017.
-
Abstract
- A needle-free vaccine/drug injector that works by virtue of the impulse of a moving shock wave is presented in this communication. The device can deliver controlled micro-volumes of liquid vaccines into skin and soft tissue targets in human with minimal invasion. The operation of the injector was investigated by delivering a dyed liquid into human skin samples and soft tissue models. The depth of penetration of the liquid was examined by histology of the targeted human skin samples. The delivery mechanics and the depth of penetration were analyzed theoretically with an elastic model for the skin and a viscoelastic model for the soft tissue targets, and a good agreement with experiments was observed. The current liquid vaccine/drug delivery technique can reduce pain, trauma and contamination, and can offer a cost-effective, needle-free, health-care solution.
- Subjects :
- 0301 basic medicine
Materials science
Biomedical Engineering
Biophysics
Phonophoresis
Health Informatics
Bioengineering
Human skin
02 engineering and technology
Impulse (physics)
High-Energy Shock Waves
law.invention
Biomaterials
03 medical and health sciences
Drug Delivery Systems
law
Humans
Syringe
Skin
Needle free
Drug injection
Vaccines
Soft tissue
Equipment Design
Injector
021001 nanoscience & nanotechnology
030104 developmental biology
Drug delivery
0210 nano-technology
Information Systems
Biomedical engineering
Subjects
Details
- ISSN :
- 18787401 and 09287329
- Volume :
- 25
- Database :
- OpenAIRE
- Journal :
- Technology and Health Care
- Accession number :
- edsair.doi.dedup.....11447ff7f12a6f95277fa7e7750d7e7c