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Evaluation of long-lasting microbial larvicide for malaria vector control in Kenya
- Source :
- Malaria journal, vol 15, iss 1, Afrane, YA; Mweresa, NG; Wanjala, CL; Gilbreath Iii, TM; Zhou, G; Lee, M-C; et al.(2016). Evaluation of long-lasting microbial larvicide for malaria vector control in Kenya.. Malaria journal, 15(1), 577. doi: 10.1186/s12936-016-1626-6. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/61b4j9d5, Malaria Journal
- Publication Year :
- 2016
- Publisher :
- eScholarship, University of California, 2016.
-
Abstract
- BackgroundOutdoor malaria transmission is becoming an increasingly important problem in malaria control in Africa. Larval control is a promising intervention as it can target both indoor and outdoor biting mosquitoes. However, the currently available biolarvicide formulations have a short effective duration, and consequently larval control incurs a high operational expense due to the requirement for frequent re-treatment of larval habitats. Formulations of biolarvicides with long-lasting effects is highly desired. A recently developed FourStar® slow-release briquet formulation of Bacillus thuringiensis israelensis and Bacillus sphaericus was evaluated to test its efficacy on malaria vectors.MethodsThe study evaluated FourStarâ„¢ briquets 180-days formulation under semi-natural and natural conditions to test their efficacy in reducing the mosquito population in western Kenya. The semi-natural habitats used the formulation dissolved in rainwater with appropriate concentrations, and second-instar larvae of Anopheles gambiae were introduced and the number of surviving larvae and pupae produced was recorded daily as the outcome. The briquets formulation was then tested in natural habitats for efficacy on pupal productivity reduction in highland and lowland sites in western Kenya. The formulation was finally tested for efficacy in reducing adult mosquito populations in randomized clusters in western Kenya highland.ResultsIn semi-natural conditions, the FourStarâ„¢ briquets 180-days formulation completely inhibited mosquito pupal production in the first 3months, and then reduced pupal productivity by 87-98% (P&nbsp
- Subjects :
- and promotion of well-being
Mosquito Control
Anopheles gambiae
Bacillus
Bacillus sphaericus
Biological larvicide
Toxicology
0302 clinical medicine
030212 general & internal medicine
2. Zero hunger
Larva
Anopheles
Bacillus thuringiensis israelensis
3. Good health
Pupa
Mosquito control
Infectious Diseases
Medical Microbiology
Public Health and Health Services
Female
Infection
030231 tropical medicine
Clinical Trials and Supportive Activities
Bacterial Toxins
Biology
Microbiology
03 medical and health sciences
Rare Diseases
Clinical Research
Tropical Medicine
parasitic diseases
Animals
Pest Control, Biological
Larvicide
Long-lasting larvicide
3.2 Interventions to alter physical and biological environmental risks
business.industry
Research
Prevention
fungi
biology.organism_classification
Prevention of disease and conditions
Biological
Survival Analysis
Kenya
Biotechnology
Malaria
Larval control
Vector-Borne Diseases
Good Health and Well Being
Parasitology
Pest Control
business
Subjects
Details
- Database :
- OpenAIRE
- Journal :
- Malaria journal, vol 15, iss 1, Afrane, YA; Mweresa, NG; Wanjala, CL; Gilbreath Iii, TM; Zhou, G; Lee, M-C; et al.(2016). Evaluation of long-lasting microbial larvicide for malaria vector control in Kenya.. Malaria journal, 15(1), 577. doi: 10.1186/s12936-016-1626-6. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/61b4j9d5, Malaria Journal
- Accession number :
- edsair.doi.dedup.....1130115af7ace2608dee3cf360d3ea43