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Multimodal Surgical Approach for Adult Patients With Chronic Intestinal Pseudo-Obstruction: Clinical and Psychosocial Long-term Outcomes
- Publication Year :
- 2018
-
Abstract
- Background Clinical and psychosocial outcomes of a multimodal surgical approach for chronic intestinal pseudo-obstruction were analyzed in 24 patients who were followed over a 2- to 12-year period in a single center after surgery or intestinal/multivisceral transplant (CTx). Methods The main reasons for surgery were sub-occlusion in surgery and parenteral nutrition–related irreversible complications with chronic intestinal failure in CTx. Results At the end of follow-up (February 2015), 45.5% of CTx patients were alive: after transplantation, improvement in intestinal function was observed including a tendency toward recovery of oral diet (81.8%) with reduced parenteral nutrition support (36.4%) in the face of significant mortality rates and financial costs (mean, 202.000 euros), frequent hospitalization (mean, 8.8/re-admissions/patient), as well as limited effects on pain or physical wellness. Conclusions Through psychological tests, transplant recipients perceived a significant improvement of mental health and emotional state, showing that emotional factors were more affected than were functional/cognitive impairment and social interaction.
- Subjects :
- Adult
Male
Intestinal pseudo-obstruction
medicine.medical_specialty
Adolescent
parenteral nutrition
030230 surgery
NO
Young Adult
03 medical and health sciences
0302 clinical medicine
parenteral nutrition, transplant, chronic intestinal pseudo-obstruction
Internal medicine
medicine
Humans
transplant
Postoperative Period
Young adult
Retrospective Studies
Transplantation
chronic intestinal pseudo-obstruction
business.industry
Mortality rate
No key words available
Intestinal Pseudo-Obstruction
Retrospective cohort study
Middle Aged
medicine.disease
Combined Modality Therapy
Chronic intestinal failure
Intestines
Intestinal Diseases
Viscera
Treatment Outcome
Parenteral nutrition
Chronic Disease
Quality of Life
Female
Parenteral Nutrition, Total
030211 gastroenterology & hepatology
Surgery
business
Psychosocial
Follow-Up Studies
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....110e0494ca8f61c46f2788a87826d02d