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Effects of tadalafil versus silodosin on voiding function in male patients with non‐neurogenic detrusor underactivity: A comparative study using propensity score matching
- Source :
- International Journal of Urology. 28:411-416
- Publication Year :
- 2021
- Publisher :
- Wiley, 2021.
-
Abstract
- OBJECTIVES To investigate and compare the effects of tadalafil and silodosin on lower urinary tract symptoms and voiding functions in men with non-neurogenic detrusor underactivity. METHODS A total of 126 treatment-naive men with lower urinary tract symptoms diagnosed as non-neurogenic detrusor underactivity received tadalafil (5 mg/day) or silodosin (8 mg/day) for 12 months. After propensity score matching, parameter changes from before administration to 12 months since treatment initiation were assessed based on subjective symptoms and urodynamic findings, including bladder contractility index and maximum urinary flow rate, and were compared between the tadalafil treatment group and the silodosin group. Detrusor underactivity was defined as bladder contractility index
- Subjects :
- Male
medicine.medical_specialty
Indoles
Urology
030232 urology & nephrology
urologic and male genital diseases
Tadalafil
03 medical and health sciences
Bladder outlet obstruction
0302 clinical medicine
Lower urinary tract symptoms
Prostate
Urinary Bladder, Underactive
medicine
Humans
Propensity Score
business.industry
Silodosin
medicine.disease
Urinary Bladder Neck Obstruction
Urodynamics
medicine.anatomical_structure
Male patient
030220 oncology & carcinogenesis
Propensity score matching
Bladder contractility
business
medicine.drug
Subjects
Details
- ISSN :
- 14422042 and 09198172
- Volume :
- 28
- Database :
- OpenAIRE
- Journal :
- International Journal of Urology
- Accession number :
- edsair.doi.dedup.....10f83fa1db529d164a1258d76cf2b480