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Supplementary Figures + Legend from Optimized Doxorubicin Chemotherapy for Diffuse Large B-cell Lymphoma Exploits Nanocarrier Delivery to Transferrin Receptors

Authors :
Jonathan H. Schatz
Roger M. Leblanc
Daniel Bilbao
Francisco Vega
Melissa W. Taggart
Austin D. Newsam
Yuguang Ban
Zhen Gao
Braulio C.L.B. Ferreira
Lingxiao Li
Evan R. Roberts
Asaad Trabolsi
Piumi Y. Liyanage
Artavazd Arumov
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Supplemental Figures 1-9. Figure S1. Carbon-Nitride Dot Synthesis. Figure S2. Characterization of CND-Dox-TF. Figure S3. CND cytotoxicity. Figure S4. Cell surface TFR1 expression and receptor recycling. Figure S5. Rapid nuclear entry by Dox after CND-Dox-TF treatment in DLBCL. Figure S6. HEK293 is a model cell line for elucidating CND-Dox-TF mechanism. Figure S7. CND-Dox-TF working dose identified. Figure S8. CND-Dox-TF has improved toxicity profile compared to Dox. Figure S9. R-nanoCHOP treatment has favorable toxicity profile in non-malignant organs.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....1092ecf2ba54526775f4544f52e93b20