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Minireview: Endocrine Disruptors: Past Lessons and Future Directions
- Source :
- Molecular endocrinology (Baltimore, Md.). 30(8)
- Publication Year :
- 2016
-
Abstract
- Within the past few decades, the concept of endocrine-disrupting chemicals (EDCs) has risen from a position of total obscurity to become a focus of dialogue, debate, and concern among scientists, physicians, regulators, and the public. The emergence and development of this field of study has not always followed a smooth path, and researchers continue to wrestle with questions about the low-dose effects and nonmonotonic dose responses seen with EDCs, their biological mechanisms of action, the true pervasiveness of these chemicals in our environment and in our bodies, and the extent of their effects on human and wildlife health. This review chronicles the development of the unique, multidisciplinary field of endocrine disruption, highlighting what we have learned about the threat of EDCs and lessons that could be relevant to other fields. It also offers perspectives on the future of the field and opportunities to better protect human health.
- Subjects :
- 0301 basic medicine
010501 environmental sciences
Biology
Endocrine Disruptors
01 natural sciences
Epigenesis, Genetic
Toxicology
03 medical and health sciences
Human health
Endocrinology
Phenols
Animals
Humans
Hormone metabolism
Benzhydryl Compounds
Molecular Biology
0105 earth and related environmental sciences
Phenols toxicity
Reproduction
Environmental ethics
Minireviews
General Medicine
Hormones
030104 developmental biology
Action (philosophy)
Signal Transduction
Subjects
Details
- ISSN :
- 19449917
- Volume :
- 30
- Issue :
- 8
- Database :
- OpenAIRE
- Journal :
- Molecular endocrinology (Baltimore, Md.)
- Accession number :
- edsair.doi.dedup.....108404b10336ceb91fd47c601b7508b4