Modern Nanomedicine in Treatment of Lung Carcinomas

Summary Backgrounds: Despite the fast development of new eff ective cytostatics and targeted therapy, the treatment effi ciency of lung cancer is still insuffi cient. The systemic administration of drugs results in a decrease in drug concentrations in tumor site, particularly due to specifi c extracellular environment in lungs. Nanotransporters could serve as a platform, protecting a drug against these undesired eff ects, which may enhance its therapeutic index and reduce side eff ects of a drug. Moreover, nanotechnologies possess the potential to improve the diagnostics of lung cancer, and thus increase a survival rate of oncologic patients. Aim: The presented study is aimed to demonstrate the possibilities provided by nanotechnologies in the fi eld of treatment and diagnostic of lung cancers and discuss the obstacles, which complicate a translation into clinical practice.