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PPARdelta-mediated macrophage activation: a matter of fat
- Source :
- Disease modelsmechanisms. 2(9-10)
- Publication Year :
- 2009
-
Abstract
- Chronic inflammation is increasingly recognized as an underlying factor in the development of several pathological disorders including obesity-associated metabolic disease, heart disease, atherosclerosis and rheumatoid arthritis. Macrophages, which are key sentinels of the innate immune system, play
- Subjects :
- Heart disease
Neuroscience (miscellaneous)
Medicine (miscellaneous)
Receptors, Cytoplasmic and Nuclear
Inflammation
Biology
Models, Biological
General Biochemistry, Genetics and Molecular Biology
Mice
PATHOLOGICAL DISORDERS
Immunology and Microbiology (miscellaneous)
medicine
Macrophage
Animals
Humans
Obesity
PPAR delta
Metabolic disease
Innate immune system
Macrophage Activation
medicine.disease
Adipose Tissue
Rheumatoid arthritis
Immunology
Cytokines
medicine.symptom
Subjects
Details
- ISSN :
- 17548411
- Volume :
- 2
- Issue :
- 9-10
- Database :
- OpenAIRE
- Journal :
- Disease modelsmechanisms
- Accession number :
- edsair.doi.dedup.....1033662b3dfab519bcd731ca03c227ed