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Demasculinisation of sexually mature male common carp, Cyprinus carpio, exposed to 4-tert-pentylphenol during spermatogenesis

Authors :
John P. Sumpter
Sylvia Gimeno
Susan Jobling
Tim Bowmer
Hans Komen
Centraal Instituut voor Voedingsonderzoek TNO
Source :
Aquatic Toxicology, 2-3, 43, 93-109
Publication Year :
1998

Abstract

Sexually mature male common carp (Cyprinus carpio) were exposed for a 3-month period to sublethal concentrations of 4-tert-pentylphenol (TPP) and to 17β-estradiol (E2) during spermatogenesis. This was part of a broad research programme investigating the effects of TPP on the life stages of the carp which might prove susceptible to endocrine disruption. Exposure of adult male carp to the pseudo-estrogen TPP, or to E2 during sexual maturation, led to elevated plasma levels of vitellogenin (P

Details

Language :
English
Database :
OpenAIRE
Journal :
Aquatic Toxicology, 2-3, 43, 93-109
Accession number :
edsair.doi.dedup.....101555234aa8d0ee0f19eaafb35273e6