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Triggering of stroke by by ambient temperature variation: A case-crossover study in Maputo, Mozambique
- Source :
- Repositório Científico de Acesso Aberto de Portugal, Repositório Científico de Acesso Aberto de Portugal (RCAAP), instacron:RCAAP
- Publication Year :
- 2015
-
Abstract
- Objectives: The effect of ambient temperature as a stroke trigger is likely to differ by type of stroke and to depend on non-transient exposures that influence the risk of this outcome. We aimed to quantify the association between ambient temperature variation and stroke, according to clinical characteristics of the events, and other risk factors for stroke. Methods: We conducted a case-crossover study based on a 1-year registry of the hospital admissions due to newly occurring ischemic and hemorrhagic stroke events in Maputo, Mozambique's capital city (N = 593). The case-period was defined as the 7 days before the stroke event, which was compared to two control periods (14–21 days and 21–28 days before the event). We computed humidity- and precipitation-adjusted odds ratios (OR) and 95% confidence intervals (95%CI) using conditional logistic regression. Results: An association between minimum temperature declines higher than 2.4 °C in any two consecutive days in the previous week and the occurrence of stroke was observed only for first events (OR = 1.43, 95%CI: 1.15–1.76). Stronger and statistically significant associations were observed for hemorrhagic stroke (OR = 1.50, 95%CI: 1.07–2.09) and among subjects not exposed to risk factors, including smoking, high serum cholesterol or atrial fibrillation. No differences in the effect of temperature were found according to the patients’ vital status 28 days after the event. Conclusions: First stroke events, especially of the hemorrhagic type, were triggered by declines in the minimum temperature between consecutive days of the preceding week.
- Subjects :
- Adult
Male
Pediatrics
medicine.medical_specialty
Time Factors
Stroke etiology
Climate
Article
03 medical and health sciences
0302 clinical medicine
CASE CROSSOVER
Risk Factors
Environmental health
Humans
Medicine
Registries
cardiovascular diseases
030212 general & internal medicine
Ambient temperature
Stroke
Mozambique
Aged
Cross-Over Studies
business.industry
Temperature
General Medicine
Middle Aged
medicine.disease
Crossover study
3. Good health
Hospitalization
Female
Surgery
Neurology (clinical)
business
Intracranial Hemorrhages
030217 neurology & neurosurgery
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Repositório Científico de Acesso Aberto de Portugal, Repositório Científico de Acesso Aberto de Portugal (RCAAP), instacron:RCAAP
- Accession number :
- edsair.doi.dedup.....100741f07c04fb5f42e0e432535ebf32