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Magnetic Solid-Phase Extraction Based on β-Cyclodextrins/Acrylic Acid Modified Magnetic Gelatin for Determination of Moxidectin in Milk Samples
- Source :
- Journal of Analytical Methods in Chemistry, Journal of Analytical Methods in Chemistry, Vol 2016 (2016)
- Publication Year :
- 2016
- Publisher :
- Hindawi Publishing Corporation, 2016.
-
Abstract
- β-Cyclodextrins/acrylic acid modified magnetic gelatin was prepared and then employed as the magnetic solid-phase extraction (MSPE) sorbent for extraction of moxidectin in milk samples. Due to the rigidity of hydrophobic cavity ofβ-cyclodextrins and carboxyl groups of acrylic acid, magnetic composites are prepared to form a complex with target molecules through various kinds of chemical reactions and then showed excellent extraction performance. This method exhibits the advantages of simplicity of implementation, short extraction time (5 min), low solvent consumption, and high extraction efficiency. A rapid, simple, and effective method for the analysis of moxidectin in milk samples was established by MSPE coupled with liquid chromatography-fluorescence detection. The limit of detection was 0.1 ng·mL−1and the recoveries from milk samples were in the range of 93.8%–112.5%. The relative standard deviation was not higher than 6.4%. In conclusion, magnetic solid-phase extraction is a simple and robust preconcentration technique that can be coupled to other analytical methods for the quantitative determination of target molecules in complex samples.
- Subjects :
- food.ingredient
Sorbent
Article Subject
General Chemical Engineering
lcsh:Analytical chemistry
02 engineering and technology
01 natural sciences
Gelatin
Chemical reaction
Analytical Chemistry
chemistry.chemical_compound
food
Solid phase extraction
Instrumentation
Acrylic acid
Detection limit
Chromatography
lcsh:QD71-142
010401 analytical chemistry
021001 nanoscience & nanotechnology
0104 chemical sciences
Computer Science Applications
Moxidectin
Solvent
chemistry
0210 nano-technology
Research Article
Subjects
Details
- Language :
- English
- ISSN :
- 20908865
- Database :
- OpenAIRE
- Journal :
- Journal of Analytical Methods in Chemistry
- Accession number :
- edsair.doi.dedup.....0ffac368c2b92b3632454ec838182b99
- Full Text :
- https://doi.org/10.1155/2016/7862152