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Risk of iodine-induced thyrotoxicosis after coronary angiography: an investigation in 788 unselected subjects
- Source :
- European journal of endocrinology. 140(3)
- Publication Year :
- 1999
-
Abstract
- In this study, the risk of iodine-induced thyrotoxicosis in unselected patients from an iodine-deficient area was investigated. The patients were consecutively enrolled. Thyroid hormone values and urinary iodine excretion were determined before, as well as 1, 4 and 12 weeks after iodine contamination by coronary angiography. Two of 788 unselected patients developed hyperthyroidism within 12 weeks. The two patients did not belong to a risk group for iodine-induced thyrotoxicosis (i.e. old people, patients with goiter or possible thyroid autonomy, low TSH). Both patients had normal TSH levels at baseline and ultrasound of the thyroid was without evidence of nodules. The study shows that in euthyroid unselected patients from an iodine-deficient area short-term iodine contamination by contrast media rarely leads to hyperthyroidism. On account of these facts, prophylactic therapy, e.g. by perchlorate or thiamazole, is not generally recommended, because the risk of side-effects is perhaps even greater than the risk of iodine-induced thyrotoxicosis.
- Subjects :
- Adult
Male
endocrine system
medicine.medical_specialty
Goiter
endocrine system diseases
Endocrinology, Diabetes and Metabolism
medicine.medical_treatment
Thyroid Gland
chemistry.chemical_element
Contrast Media
Thyrotropin
Iodine
Coronary Angiography
Iodide Peroxidase
Endocrinology
Antithyroid Agents
Hypothyroidism
Internal medicine
medicine
Humans
Euthyroid
Aged
Aged, 80 and over
Methimazole
medicine.diagnostic_test
business.industry
Antithyroid agent
Thyroid
General Medicine
Middle Aged
medicine.disease
Iodine deficiency
Thyroxine
medicine.anatomical_structure
Thyrotoxicosis
chemistry
Angiography
Female
business
Hormone
Subjects
Details
- ISSN :
- 08044643
- Volume :
- 140
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- European journal of endocrinology
- Accession number :
- edsair.doi.dedup.....0fe7304c3feb0ac68cd480e26093c061