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Keratinocyte cancer with incidental perineural invasion: A registry analysis of management and 5-year outcomes
- Source :
- The Australasian journal of dermatologyReferences. 61(3)
- Publication Year :
- 2019
-
Abstract
- Background/Objectives: Perineural invasion within keratinocyte cancer is a hallmark of tumour aggression, and a definitive treatment paradigm for this condition remains undetermined. Our aim was to investigate the treatment and outcomes of keratinocyte cancer with incidental perineural invasion within two skin cancer databases to refine treatment protocols. Methods: We retrospectively assessed the Queensland Perineural Invasion Registry for surgery, histopathology, adjuvant radiotherapy and recurrence of keratinocyte cancer five years post‐definitive treatment. We also reviewed the Princess Alexandra Hospital Head and Neck clinical perineural invasion database, specifically looking at surgical margins and adjuvant radiotherapy of cutaneous squamous cell carcinoma (cSCC) with incidental perineural invasion in the primary lesion. Results: There was no recurrence at 5 years in the Perineural Invasion Registry. Basal cell carcinoma (BCC) lesions with nerves
- Subjects :
- medicine.medical_specialty
Skin Neoplasms
Perineural invasion
Dermatology
030207 dermatology & venereal diseases
03 medical and health sciences
0302 clinical medicine
medicine
Humans
Basal cell carcinoma
Neoplasm Invasiveness
Peripheral Nerves
Registries
Retrospective Studies
Adjuvant radiotherapy
business.industry
Cancer
Margins of Excision
Primary lesion
medicine.disease
Mohs Surgery
medicine.anatomical_structure
Carcinoma, Basal Cell
Head and Neck Neoplasms
030220 oncology & carcinogenesis
Carcinoma, Squamous Cell
Histopathology
Radiotherapy, Adjuvant
Radiology
Skin cancer
Neoplasm Recurrence, Local
Keratinocyte
business
Subjects
Details
- ISSN :
- 14400960
- Volume :
- 61
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- The Australasian journal of dermatologyReferences
- Accession number :
- edsair.doi.dedup.....0fc8b18f66cdf4e1309ebcd51208e994