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Efficacy of image-guided synovial biopsy
- Source :
- Skeletal Radiology. 49:921-928
- Publication Year :
- 2020
- Publisher :
- Springer Science and Business Media LLC, 2020.
-
Abstract
- A variety of benign and neoplastic lesions can affect the synovium, including pigmented villonodular synovitis (PVNS) and synovial chondromatosis. Prior to surgical resection, accurate characterization of synovial lesions is necessary for appropriate treatment planning. Additionally, recent advances in potential medical therapies for PVNS could decrease or eliminate the need for surgery in some cases. Such treatment options demand accurate characterization of synovial lesions prior to treatment. Institutional IRB approval was obtained. We identified 54 synovial biopsies performed at our institution using a comprehensive database search under ultrasound (US) or computed tomography (CT) guidance. Cases were reviewed for pre-procedure imaging, location, biopsy approach, biopsy results, post-procedure complications, and surgical pathology if synovectomy was performed. A total of 54 image-guided synovial biopsies were performed, 36 using CT guidance and 18 using US guidance. Six different anatomic locations were biopsied (the hip, knee, shoulder, elbow, ankle, and temporomandibular joint). Synovial tissue was obtained in 89% of cases (48/54). CT-guided biopsies had a positive yield of 86% (31/36) and US-guided biopsies had a positive yield of 94% (17/18). Surgical pathology was obtained in 30 of the cases and image-guided biopsy concordance was 90% (27/30). Of the patients taken for synovectomy, biopsy concordance of suspected neoplastic lesions was 100% (23/23). In cases of suspected neoplasm, the concordance between image-guided biopsy and surgical pathology was 96% (22/23). There were no reported complications. Image-guided biopsy of synovial lesions is safe and effective for establishing a definitive diagnosis prior to surgical or other intervention.
- Subjects :
- Adult
Image-Guided Biopsy
Male
medicine.medical_specialty
Adolescent
medicine.medical_treatment
Synovectomy
Synovitis, Pigmented Villonodular
Radiography, Interventional
030218 nuclear medicine & medical imaging
Surgical pathology
03 medical and health sciences
0302 clinical medicine
Synovial chondromatosis
Biopsy
Humans
Medicine
Radiology, Nuclear Medicine and imaging
Radiation treatment planning
Ultrasonography, Interventional
Aged
Retrospective Studies
Aged, 80 and over
030203 arthritis & rheumatology
medicine.diagnostic_test
business.industry
Middle Aged
medicine.disease
Temporomandibular joint
medicine.anatomical_structure
Pigmented villonodular synovitis
Orthopedic surgery
Female
Radiology
Tomography, X-Ray Computed
business
Chondromatosis, Synovial
Subjects
Details
- ISSN :
- 14322161 and 03642348
- Volume :
- 49
- Database :
- OpenAIRE
- Journal :
- Skeletal Radiology
- Accession number :
- edsair.doi.dedup.....0f8fb2b6e4a28c98f9bf82336a9acf1c