Back to Search
Start Over
Intravenous Ionic Contrast Media Cause Local Prostacyclin Release in Man
- Source :
- Europe PubMed Central
- Publication Year :
- 1985
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 1985.
-
Abstract
- The effect of intravenous administration of ionic contrast media on local release of prostacyclin (PGI2) was investigated in man. Iodamide and ioxaglate, high- and low-osmolality contrast media, respectively, both significantly increased PGI2 levels at the site of injection. Iodamide was the most active, whereas an identical volume of isotonic saline had no effect. This study suggests that local formation of PGI2 may adequately reflect the degree of endothelial irritation that is caused by contrast media and that depends in part on their osmolality.
- Subjects :
- Iodamide
medicine.medical_specialty
Isotonic saline
Ioxaglic acid
Contrast Media
Prostacyclin
medicine.disease_cause
Osmolar Concentration
chemistry.chemical_compound
Triiodobenzoic Acids
Internal medicine
Ioxaglic Acid
medicine
Humans
Radiology, Nuclear Medicine and imaging
IONIC CONTRAST MEDIA
General Medicine
Epoprostenol
Stimulation, Chemical
Endocrinology
chemistry
Anesthesia
Injections, Intravenous
cardiovascular system
Iodobenzoates
lipids (amino acids, peptides, and proteins)
Irritation
medicine.drug
Subjects
Details
- ISSN :
- 00209996
- Volume :
- 20
- Database :
- OpenAIRE
- Journal :
- Investigative Radiology
- Accession number :
- edsair.doi.dedup.....0f87480764f94ca535b6548306a80a3b