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Larvicidal and Pupicidal Activities of Alizarin Isolated from Roots of Rubia cordifolia Against Culex quinquefasciatus Say and Aedes aegypti (L.) (Diptera: Culicidae)
- Source :
- Neotropical entomology. 45(4)
- Publication Year :
- 2015
-
Abstract
- The mosquitocidal activities of different fractions and a compound alizarin from the methanol extract of Rubia cordifolia roots were evaluated on larvae and pupae of Culex quinquefasciatus Say and Aedes aegypti (L.) (Diptera: Culicidae). Larvae and pupae were exposed to concentrations of 2.5, 5.0, 7.5 and 10 ppm for fractions and 0.5, 1.0, 1.5 and 2.0 ppm for compound. After 24 h, the mortality was assessed and the LC50 and LC90 values were estimated for larvae and pupae. Among the 23 fractions screened, fraction 2 from the methanol extract of R. cordifolia showed good mosquitocidal activity against C. quinquefasciatus and A. aegypti. LC50 and LC90 values of fraction 2 were 3.53 and 7.26 ppm for C. quinquefasciatus and 3.86 and 8.28 ppm for A. aegypti larvae, and 3.76 and 7.50 ppm for C. quinquefasciatus and 3.92 and 8.05 ppm for A. aegypti pupae, respectively. Further, the isolated compound alizarin presented good larvicidal and pupicidal activities. LC50 and LC90 values of alizarin for larvae were 0.81 and 3.86 ppm against C. quinquefasciatus and 1.31 and 6.04 ppm for A. aegypti larvae, respectively. Similarly, the LC50 and LC90 values of alizarin for pupae were 1.97 and 4.79 ppm for C. quinquefasciatus and 2.05 and 5.59 ppm for A. aegypti pupae, respectively. The structure of the isolated compound was identified on the basis of spectroscopic analysis and compared with reported spectral data. The results indicated that alizarin could be used as a potential larvicide and pupicide.
- Subjects :
- 0301 basic medicine
Veterinary medicine
Insecticides
Mosquito Control
Culex
030231 tropical medicine
Anthraquinones
Aedes aegypti
Alizarin
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Rubia cordifolia
Aedes
Botany
Anopheles
Animals
Larvicide
biology
Plant Extracts
Rubia
biology.organism_classification
Culex quinquefasciatus
Plant Leaves
030104 developmental biology
chemistry
Insect Science
Larva
Subjects
Details
- ISSN :
- 16788052
- Volume :
- 45
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Neotropical entomology
- Accession number :
- edsair.doi.dedup.....0f2af7cf147eace7fc27a7ae62f4cb8e