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Construction of molecular logic gates using heavy metal ions as inputs based on catalytic hairpin assembly and CRISPR-Cas12a

Construction of molecular logic gates using heavy metal ions as inputs based on catalytic hairpin assembly and CRISPR-Cas12a

Authors :
Jiafeng Pan
Fang Deng
Zhi Liu
Lingwen Zeng
Junhua Chen
Source :
Talanta. 255:124210
Publication Year :
2023
Publisher :
Elsevier BV, 2023.

Abstract

We successfully constructed several molecular logic gates using heavy metal ions as inputs based on catalytic hairpin assembly (CHA) and CRISPR-Cas12a. The corresponding DNAzymes were used to recognize heavy metal ions (Hg

Subjects

Subjects :
Analytical Chemistry

Details

ISSN :
00399140
Volume :
255
Database :
OpenAIRE
Journal :
Talanta
Accession number :
edsair.doi.dedup.....0ed986cdb5c19d09b241e520c708f09e
Full Text :
https://doi.org/10.1016/j.talanta.2022.124210
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