Supplementary Figures from Pathogenic Epigenetic Consequences of Genetic Alterations in IDH-Wild-Type Diffuse Astrocytic Gliomas

SF1: Loss of p53 and NF1 expression in MADM GFP-positive precancerous cells and tumor cells; SF2: Clustering analysis of gene expression status in human gliomas; SF3: Expression levels of epigenetic genes in MADM tumors, human IDH-wild-type DAGs-MF and DAGs-nonMF; SF4: Histone modifications and expression status in Ezh2 wild-type MADM tumors; SF5: Copy number analysis of genes located on chromosomes 7 and 10 in the TM31 cell line; SF6: Relationship between Ezh2 expression and RAS signaling pathway; SF7: Inhibition of EZH2/PRC2 as a specific treatment strategy for IDH-wild-type DAGs-nonMF.