Back to Search
Start Over
Harnessing the Properties of Natural Products
- Source :
- Annual review of pharmacology and toxicology. 58
- Publication Year :
- 2017
-
Abstract
- Natural products (NPs) have been used as traditional medicines since antiquity. With more than 1060 estimated compounds with molecular weights less than 500 Da representing chemical space, NPs occupy a very small percentage; however, they are significantly overrepresented in biologically relevant chemical space. The classical approach concentrates on identifying one or more NPs with biological activity from a source organism. There is much more to be learned from NPs than we can discover this narrow view. In this review, we discuss ways to harness the global properties of NPs.
- Subjects :
- 0301 basic medicine
Pharmacology
Biological Products
010405 organic chemistry
Nanotechnology
Biology
Toxicology
01 natural sciences
Natural (archaeology)
Chemical space
0104 chemical sciences
Molecular Weight
Small Molecule Libraries
03 medical and health sciences
030104 developmental biology
Drug Discovery
Animals
Humans
Biochemical engineering
Biological sciences
Organism
Subjects
Details
- ISSN :
- 15454304
- Volume :
- 58
- Database :
- OpenAIRE
- Journal :
- Annual review of pharmacology and toxicology
- Accession number :
- edsair.doi.dedup.....0ea43565c92528f5ea2742ae8949cf88