Back to Search
Start Over
Cholecystokinin: How many functions? Observations in seabreams
- Source :
- General and comparative endocrinology, 205 (2014): 166–167. doi:10.1016/j.ygcen.2014.02.019, info:cnr-pdr/source/autori:Micale V.; Campo S.; D'Ascola A.; Guerrera M.C.; Levanti M.B.; Germana A.; Muglia U./titolo:Cholecystokinin: How many functions? Observations in seabreams/doi:10.1016%2Fj.ygcen.2014.02.019/rivista:General and comparative endocrinology (Print)/anno:2014/pagina_da:166/pagina_a:167/intervallo_pagine:166–167/volume:205
- Publication Year :
- 2014
- Publisher :
- Elsevier BV, 2014.
-
Abstract
- A short overview on the regional distribution of the gastro-intestinal peptide hormone cholecystokin (CCK) in fish is presented. In particular, the results of molecular and immunological studies on seabreams, Diplodus puntazzo and Diplodus sargus, are reported, which, by demonstrating CCK in the hindgut, open new questions regarding the functional role of this hormone in that part of the intestine. The putative involvement of hindgut CCK in the feedback control of digestive processes was tested by measuring CCK gene and protein expression in fed and fasted fish. The results of this study led to hypothesize different roles for the two CCK isoforms in D. sargus, one of which related to regulation of digestive processes from pyloric caeca through hindgut. On the other hand, a functional role alternative to regulation of digestive processes may be inferred for the other isoform.
- Subjects :
- Gene isoform
medicine.medical_specialty
Diplodus puntazzo
Diplodus sargus
Peptide hormone
digestive system
Endocrinology
Seabream
Internal medicine
medicine
Animals
Gut
Intestinal Mucosa
Cholecystokinin
biology
digestive, oral, and skin physiology
Hindgut
Diplodus
biology.organism_classification
Sea Bream
Animal Science and Zoology
SEABREAM
hormones, hormone substitutes, and hormone antagonists
Sargus
Hormone
Subjects
Details
- ISSN :
- 00166480
- Volume :
- 205
- Database :
- OpenAIRE
- Journal :
- General and Comparative Endocrinology
- Accession number :
- edsair.doi.dedup.....0e95a88a26b05a1b7d247b2282ee63ab