Safety and Efficacy Outcomes of Bioresorbable Scaffolds in Long Segment Coronary Lesions

Introduction:Thereis limited knowledge about the use of bioresorbable scaffolds (BRSs) in longsegment coronary artery lesions. We aimed to evaluate the clinical outcomes ofBRS-BRS and drug eluting stents (DESs)-BRS overlapping applications.Patientsand Methods: Cross-sectional, single-center study between 2013 and2016 enrolled 97 patients and 100 lesions scheduled for BRS placement in longsegment lesions (> 28 mm). BRS-BRS overlap was performed in 30 patients and30 lesions, DES-BRS overlap was performed in 67 patients and 70 lesions. Acuteprocedural success and major adverse cardiac events (MACE) (death, stent thrombosis,and target lesion reintervention) were assessed.Results: Acuteprocedural success was 97.1% in the overall group. MACE was observed in 6patients (6.2%) in the entire group, 4 (5.9%) in the DES-BRS group, and 2(6.6%) in the BRS-BRS group.Conclusion: BRS use might be a safeand effective option for the treatment of long segment lesions. Both BRS-BRSoverlap and BRS-DES overlap may be performed with short overlap segment.
Giriş: Uzun segment lezyonlarda biyoeriyebilen stentlerin (BRS) kullanımı ileilgili sınırlı bilgimiz olduğundan hem BRS-BRS hem de İlaç salınımlı metalstent (DES)-BRS overlap uygulanan hastaların klinik sonuçlarını değerlendirmeyiplanladık.Hastalar veYöntem: Tek merkezli, kesitsel planlanan; Ocak 2013-Haziran 2016tarihleri arasında uzun segment lezyonlara (> 28 mm) BRS yerleştirilmesiplanlanan 97 hasta ve 100 lezyon çalışmaya alındı. Otuz hasta ve 30 lezyondaBRS-BRS overlap uygulanırken , 67 hasta 70 lezyona DES-BRS overlap uygulandı.Akut işlem başarısı ve MACE (ölüm, stent trombozu, hedef damara yeniden girişim)değerlendirildi.Bulgular: Akut işlem başarısı %97.1 idi. Tüm hasta grubunda toplam MACE 6 (%6.2)hastada gelişirken, DES-BRS grubunda 4 (%5.9), BRS-BRS grubunda 2 (%6.6)hastada MACE gerçekleşti.Sonuç: Uzun segment lezyonlardaBRS kullanımı seçenek olarak değerlendirilebilinir. BRS-BRS veya BRS-DESoverlap yapacak şekilde yerleştiriken kısa segment overlap olacak şekildegerçekleştirilmelidir.