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The immunomodulatory drug Leflunomide inhibits cell cycle progression of B-CLL cells
- Source :
- Leukemia. 22:635-638
- Publication Year :
- 2007
- Publisher :
- Springer Science and Business Media LLC, 2007.
- Subjects :
- DNA Replication
Oxidoreductases Acting on CH-CH Group Donors
Cancer Research
Toluidines
Receptors, Prostaglandin
Cell cycle progression
Dihydroorotate Dehydrogenase
Hydroxybutyrates
Immunomodulatory drug
Apoptosis
Tumor cells
Cyclin A
Biology
Retinoblastoma Protein
Cyclins
Nitriles
Tumor Cells, Cultured
medicine
Humans
Immunologic Factors
Prodrugs
Cyclin D3
Phosphorylation
Receptors, Immunologic
Receptor
Leflunomide
B-Lymphocytes
ZAP-70 Protein-Tyrosine Kinase
Cyclin-Dependent Kinase 2
G1 Phase
Isoxazoles
Hematology
medicine.disease
Leukemia, Lymphocytic, Chronic, B-Cell
Neoplasm Proteins
Leukemia
Oncology
Crotonates
Protein processing
Immunology
Cancer research
Drug Screening Assays, Antitumor
Protein Processing, Post-Translational
medicine.drug
Subjects
Details
- ISSN :
- 14765551 and 08876924
- Volume :
- 22
- Database :
- OpenAIRE
- Journal :
- Leukemia
- Accession number :
- edsair.doi.dedup.....0e3e85bdbf036d2caa09e821279e9d9b
- Full Text :
- https://doi.org/10.1038/sj.leu.2404922