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Endogenous cortisol exerts antiemetic effect similar to that of exogenous corticosteroids
- Source :
- British Journal of Cancer
- Publication Year :
- 1993
- Publisher :
- Springer Science and Business Media LLC, 1993.
-
Abstract
- Lower pre-chemotherapy night time cortisol excretion predicted more severe cisplatin induced nausea and vomiting in 42 ovarian cancer patients receiving ondansetron as a single antiemetic agent. Dexamethasone administration added to the antiemetic effect of ondansetron principally in patients who had low excretion of cortisol.
- Subjects :
- Adult
endocrine system
Cancer Research
Antiemetic Agent
medicine.medical_specialty
Hydrocortisone
Nausea
medicine.drug_class
Dexamethasone
Ondansetron
Internal medicine
Antineoplastic Combined Chemotherapy Protocols
medicine
Humans
Antiemetic
Melphalan
Aged
Ovarian Neoplasms
business.industry
Middle Aged
Endocrinology
Oncology
Doxorubicin
Vomiting
Antiemetics
Female
Cisplatin
medicine.symptom
business
Glucocorticoid
Research Article
medicine.drug
Subjects
Details
- ISSN :
- 15321827 and 00070920
- Volume :
- 68
- Database :
- OpenAIRE
- Journal :
- British Journal of Cancer
- Accession number :
- edsair.doi.dedup.....0e337f24d3fb0d327662eac524a90e5a