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The evaluation of non-anesthetic computed tomography for detection of pulmonary parenchyma in feline mammary gland carcinoma: a preliminary study
- Source :
- BMC Veterinary Research, Vol 17, Iss 1, Pp 1-10 (2021), BMC Veterinary Research
- Publication Year :
- 2021
- Publisher :
- BMC, 2021.
-
Abstract
- Background Thoracic radiography in awake cats is a common procedure for the evaluation of pulmonary metastasis in feline mammary gland carcinoma (MGC). However, due to poor sensitivity, computed tomography (CT) is progressively taking its place. To perform CT in animals, general anesthesia is normally preferred but can cause lung atelectasis, affecting lung interpretation. Besides, MGC is often found in senile cats that are concurrently affected with other diseases, increasing anesthetic risk. Therefore, this study was aimed at comparing the effect of anesthesia on lung atelectasis observed through CT in clinically healthy cats and comparing the feasibility of non-anesthetic CT with non-anesthetic radiography in the detection of lung lesions in feline MGC. Thoracic CTs from anesthetized, clinically healthy cats and non-anesthetized either clinically healthy cats or MGC-affected cats were reviewed. In clinically healthy cats, motion artifacts and characteristics of lung atelectasis were observed and compared. In MGC-affected cats, motion artifacts were observed and compared to clinically healthy cats, and the number of MGC-affected cats, the number and characteristics of lung lesions were compared between non-anesthetic thoracic CT and radiography. Results Anesthesia significantly increased lung CT attenuation (P = 0.0047) and was significantly correlated with lung atelectasis (OR = 15; CI 2.02–111.18; P = 0.0081), particularly of the cranial lung lobe. Nonetheless, significantly higher motion artifacts in the caudal thoracic area were found in non-anesthetized healthy cats (P = 0.0146), but comparable low motion artifacts were observed in anesthetized healthy and MGC-affected cats. Non-anesthetic CT revealed higher numbers of MGC-affected cats and pulmonary nodules with a significantly lower nodular diameter (P = 0.0041) than those observed on radiographs. The smallest nodular diameters detected on radiographs and CT were 2.5 and 1.0 mm, respectively. Furthermore, CT showed additional information such as intra-thoracic lymphadenopathy, that could not be seen on radiographs. Conclusions Despite the motion artifacts, CT without anesthesia is a sensitive technique as it provides better lung inflation. Furthermore, compared to non-anesthetic radiography, non-anesthetic CT provided more information such as higher number of pulmonary nodules of a smaller size, including more distinct intra-thoracic lesions, such as lymphadenopathy, in MGC-affected cats.
- Subjects :
- Male
medicine.medical_specialty
Pulmonary Atelectasis
Lung Neoplasms
040301 veterinary sciences
Radiography
Veterinary medicine
Mammary gland
Computed tomography
Atelectasis
Mammary Neoplasms, Animal
Cat Diseases
0403 veterinary science
03 medical and health sciences
0302 clinical medicine
SF600-1100
medicine
Carcinoma
Animals
Anesthesia
Lung
CATS
General Veterinary
medicine.diagnostic_test
business.industry
Research
Cat
04 agricultural and veterinary sciences
General Medicine
medicine.disease
Mammary gland carcinoma
medicine.anatomical_structure
030220 oncology & carcinogenesis
Anesthetic
Cats
Female
Radiography, Thoracic
Radiology
business
Artifacts
Tomography, X-Ray Computed
medicine.drug
Subjects
Details
- Language :
- English
- ISSN :
- 17466148
- Volume :
- 17
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- BMC Veterinary Research
- Accession number :
- edsair.doi.dedup.....0e2e623b28f2fb004171e23591dde2c5