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Neuroimaging Studies in Insomnia
- Source :
- Current Psychiatry Reports. 15
- Publication Year :
- 2013
- Publisher :
- Springer Science and Business Media LLC, 2013.
-
Abstract
- Chronic insomnia is one of the most prevalent psychiatric disorders and has a significant impact on individual's health. However, the pathophysiology of the disorder is poorly understood. The current review focuses on neuroimaging findings in insomnia. In summary, the current data suggest the following: (1) insomnia is characterized by corticolimbic overactivity during sleep and wakefulness that interferes with sleep initiation and/or maintenance; (2) insomnia patients' daytime performance is associated with a hypoactivation of task-related areas; (3) neurochemically, insomnia patients are probably characterized by reduced cortical GABA levels; (4) insomnia may be associated with abnormal brain morphometry in the frontal cortex, hippocampus and/or anterior cingulate cortex. Future investigations should include larger sample sizes or longitudinal within-subject comparisons. Other possible methodological improvements are discussed.
- Subjects :
- Brain morphometry
Brain
Hippocampus
Neuroimaging
Sleep in non-human animals
Pathophysiology
Psychiatry and Mental health
medicine.anatomical_structure
Sleep Initiation and Maintenance Disorders
mental disorders
Insomnia
medicine
Humans
Wakefulness
medicine.symptom
Psychology
Neuroscience
Anterior cingulate cortex
Clinical psychology
Subjects
Details
- ISSN :
- 15351645 and 15233812
- Volume :
- 15
- Database :
- OpenAIRE
- Journal :
- Current Psychiatry Reports
- Accession number :
- edsair.doi.dedup.....0df04dc7e8d05570283ecc7c588b18bd
- Full Text :
- https://doi.org/10.1007/s11920-013-0405-0