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Implantation of p(HEMA)-collagen composite into bone
- Source :
- Biomaterials. 13(9)
- Publication Year :
- 1992
-
Abstract
- The replacement of bone defects is very important in clinical practice. This study compares biological properties of poly(2-hydroxyethyl methacrylate)-collagen composite with those exhibited by pure p(HEMA), an insoluble fraction of calf skin collagen (ISC-40) and demineralized bone matrix after implantation into pig or dog femurs. The levels of biodegradation or destruction of implants and healing of bone defects were studied using X-ray photography, histology and enzyme histochemistry. The results indicated a significant effect of collagen on biological destruction of the p(HEMA)-composite implants; even a minute amount of collagen influences this process dramatically. A stimulatory action of collagen on new bone formation may be of importance in bone defect healing.
- Subjects :
- Materials science
Swine
Composite number
Biophysics
Dentistry
Bioengineering
Biocompatible Materials
Methacrylate
Bone and Bones
Biomaterials
Dogs
Biological property
Animals
Humans
Bone formation
Polyhydroxyethyl Methacrylate
biology
Demineralized bone matrix
business.industry
Fissipedia
Histology
Prostheses and Implants
biology.organism_classification
Bone defect
Prosthesis Failure
Mechanics of Materials
Ceramics and Composites
Swine, Miniature
Cattle
Collagen
business
Biomedical engineering
Subjects
Details
- ISSN :
- 01429612
- Volume :
- 13
- Issue :
- 9
- Database :
- OpenAIRE
- Journal :
- Biomaterials
- Accession number :
- edsair.doi.dedup.....0dda9c427ba66a5bf55960681b6439e8