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Reduction of Postoperative Complication Rate with the Use of Early Oral Feeding in Gynecologic Oncologic Patients Undergoing a Major Surgery: A Randomized Controlled Trial
- Source :
- Annals of Surgical Oncology. 16:3101-3110
- Publication Year :
- 2009
- Publisher :
- Springer Science and Business Media LLC, 2009.
-
Abstract
- Background: A randomized controlled trial was performed to assess the outcome of early oral postoperative feeding (EOF) compared with traditional oral feeding (TOF) in gynecologic oncology patients undergoing a complex laparotomy, including upper abdominal surgery. Methods: Patients aged 18-75 years, undergoing an elective laparotomy and with a preoperative suspicion of gynecologic malignancy, were eligible. Exclusion criteria included infectious conditions, intestinal obstruction, severe malnutrition, American Society of Anesthesiologists score ≥ 4, intestinal resection, and postoperative stay in the intensive care unit lasting >24 h. Patients allocated to EOF received liquid diet in the first postoperative day and then regular diet. Patients received traditional feeding scheme until resolution of postoperative ileus to start liquid diet. The primary end-point of the trial was length of hospital stay. Results: Between January 1, 2007, and November 17, 2007, a total of 143 patients were randomized to receive either EOF or TOF. Hospital stay for patients who received EOF (n = 71) was 4.7 vs. 5.8 days for the TOF group (n = 72) (P = 0.006). The mean level of postoperative satisfaction was significantly higher in the EOF group (82.8 vs. 71.7 mm, P ≤ 0.001). Patients who received the TOF scheme had significantly higher overall postoperative complications (39 vs. 17% in EOF group, P = 0.003) and infective complications (14% in TOF group vs. 3% in EOF group, P = 0.017). Variables such as nausea and vomiting, analgesic and antiemetic requirement as well as level of pain and quality of life were not different between groups. Conclusions: On the basis of these findings, the policy of EOF should be used after a complex gynecologic oncologic laparotomy
- Subjects :
- Adult
medicine.medical_specialty
Time Factors
Adolescent
Genital Neoplasms, Female
medicine.medical_treatment
Gynecologic oncology
law.invention
Eating
Young Adult
Postoperative Complications
Quality of life
Randomized controlled trial
Surgical oncology
law
Laparotomy
medicine
Humans
Young adult
Survival rate
Aged
Neoplasm Staging
Pain, Postoperative
business.industry
Postoperative complication
Length of Stay
Middle Aged
Prognosis
Surgery
Survival Rate
Treatment Outcome
early oral feeding
Oncology
Anesthesia
Quality of Life
Female
business
Follow-Up Studies
Subjects
Details
- ISSN :
- 15344681 and 10689265
- Volume :
- 16
- Database :
- OpenAIRE
- Journal :
- Annals of Surgical Oncology
- Accession number :
- edsair.doi.dedup.....0dd7cdd4774e5d5abb55fcf9370e3160