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Multi-modal treatment with peptide vaccine, metronomic cyclophosphamide and anti-PD1 monoclonal antibody provides effective control of tumors in multiple models

Authors :
Neil L Berinstein
Genevieve Weir
Mohan Karkada
Robert S. Liwski
Marianne M. Stanford
Marc Mansour
Olga Hrytsenko
Source :
Journal for Immunotherapy of Cancer
Publisher :
Springer Nature

Abstract

Meeting abstracts Future cancer immunotherapies will combine multiple treatments to improve immune responses to cancer through synergistic, multi-modal mechanisms. In a Phase I clinical trial, we found that the immune response to a peptide vaccine targeting survivin, DPX-Survivac, by ovarian cancer

Details

Language :
English
ISSN :
20511426
Volume :
2
Issue :
Suppl 3
Database :
OpenAIRE
Journal :
Journal for ImmunoTherapy of Cancer
Accession number :
edsair.doi.dedup.....0db9b1b5c33d946735a1663222279f23
Full Text :
https://doi.org/10.1186/2051-1426-2-s3-p130