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Multi-modal treatment with peptide vaccine, metronomic cyclophosphamide and anti-PD1 monoclonal antibody provides effective control of tumors in multiple models
- Source :
- Journal for Immunotherapy of Cancer
- Publisher :
- Springer Nature
-
Abstract
- Meeting abstracts Future cancer immunotherapies will combine multiple treatments to improve immune responses to cancer through synergistic, multi-modal mechanisms. In a Phase I clinical trial, we found that the immune response to a peptide vaccine targeting survivin, DPX-Survivac, by ovarian cancer
- Subjects :
- Pharmacology
Cancer Research
business.industry
Immunology
Cancer
Phases of clinical research
biochemical phenomena, metabolism, and nutrition
medicine.disease
Anti-PD1 Monoclonal Antibody
Immune system
Oncology
Poster Presentation
Survivin
Cancer research
Peptide vaccine
Molecular Medicine
Immunology and Allergy
Medicine
business
Ovarian cancer
Metronomic cyclophosphamide
Subjects
Details
- Language :
- English
- ISSN :
- 20511426
- Volume :
- 2
- Issue :
- Suppl 3
- Database :
- OpenAIRE
- Journal :
- Journal for ImmunoTherapy of Cancer
- Accession number :
- edsair.doi.dedup.....0db9b1b5c33d946735a1663222279f23
- Full Text :
- https://doi.org/10.1186/2051-1426-2-s3-p130