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Effects of Sedation with Medetomidine and Dexmedetomidine on Doppler Measurements of Ovarian Artery Blood Flow in Bitches
- Source :
- Animals : an Open Access Journal from MDPI, Animals, Volume 11, Issue 2, Animals, Vol 11, Iss 538, p 538 (2021)
- Publication Year :
- 2021
- Publisher :
- MDPI, 2021.
-
Abstract
- The aim was to evaluate if medetomidine and dexmedetomidine affected arterial ovarian blood flow in dogs. The dogs were randomly assigned to two different groups. In Group 1, medetomidine (10 µg/kg) was administered intramuscularly and, in Group 2, dexmedetomidine (5 µg/kg) was used. After a preliminary exam, arterial blood pressure (BP) was measured and a duplex Doppler ultrasonographic examination of both ovarian arteries was performed. Twenty minutes after the administration of medetomidine or dexmedetomidine, BP and ovarian Doppler ultrasonography were repeated. High quality tracings of ovarian artery flow velocity were obtained in all dogs and Doppler parameters: Peak Systolic Velocity (PSV), End Diastolic Velocity (EDV) and Resistive Index (RI) were measured before and after drug administration in the left (LO) and right (RO) ovaries. PSV and EDV values decreased significantly after drug administration (p &lt<br />0.05) compared to the non-sedated values, but no differences were found between the LO and RO (p &gt<br />0.05). The RI was not affected by drugs administration in neither of the groups studied (p &gt<br />0.05). In conclusion, the administration of medetomidine or dexmedetomidine causes a decrease in blood flow velocity in the ovarian artery and may be a good choice to avoid excessive bleeding prior surgeries in which ovariectomy.
- Subjects :
- 040301 veterinary sciences
Sedation
bitches
medetomidine
Diastole
Doppler measurements
Ovarian artery
Article
0403 veterinary science
03 medical and health sciences
medicine.artery
lcsh:Zoology
Medicine
lcsh:QL1-991
Dexmedetomidine
030304 developmental biology
0303 health sciences
lcsh:Veterinary medicine
General Veterinary
business.industry
Doppler
dexmedetomidine
04 agricultural and veterinary sciences
Blood flow
Medetomidine
Blood pressure
Anesthesia
ovarian artery
lcsh:SF600-1100
Animal Science and Zoology
medicine.symptom
business
medicine.drug
Subjects
Details
- Language :
- English
- ISSN :
- 20762615
- Volume :
- 11
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Animals : an Open Access Journal from MDPI
- Accession number :
- edsair.doi.dedup.....0db966d9149a6e2a3b4fb2b58dc19c61