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Reverse genetics tools in zebrafish: A forward dive into endocrinology
- Source :
- General and comparative endocrinology
- Publication Year :
- 2013
- Publisher :
- Elsevier BV, 2013.
-
Abstract
- The zebrafish is a powerful genetic model organism. In recent years, zebrafish has been increasingly used to model human diseases. Due to a number of recent technological advancements, the genetic tool box is now also stocked with sophisticated transgenic and reverse genetic tools. Here, we focus on both commonly used and recently established reverse genetic and transgenic tools available in zebrafish. These new developments make the zebrafish an even more attractive animal model in comparative endocrinology.
- Subjects :
- TILLING
animal structures
Transgene
610 Medicine & health
Computational biology
Animals, Genetically Modified
03 medical and health sciences
0302 clinical medicine
Endocrinology
Animal model
Genetic model
Animals
Zebrafish
Organism
030304 developmental biology
Genetics
0303 health sciences
Transcription activator-like effector nuclease
biology
fungi
biology.organism_classification
10124 Institute of Molecular Life Sciences
Reverse Genetics
Reverse genetics
1310 Endocrinology
10076 Center for Integrative Human Physiology
Models, Animal
embryonic structures
570 Life sciences
Animal Science and Zoology
1103 Animal Science and Zoology
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 00166480
- Volume :
- 188
- Database :
- OpenAIRE
- Journal :
- General and Comparative Endocrinology
- Accession number :
- edsair.doi.dedup.....0da203b8aaa7d0027884df41a4e1809a
- Full Text :
- https://doi.org/10.1016/j.ygcen.2013.02.002