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Natural variation of H3K27me3 modification in two Arabidopsis accessions and their hybrid
- Source :
- Journal of integrative plant biology. 58(5)
- Publication Year :
- 2015
-
Abstract
- Histone modifications affect gene expression, but the mechanism and biological consequence of natural variation in histone modifications remain unclear. Here, we generated genome-wide integrated maps of H3K27me3 modification and transcriptome for Col, C24 and their F1 hybrid. A total of 1,828 genomic regions showing variation in H3K27me3 modification between Col and C24 were identified, most of which were associated with genic regions. Natural variation of H3K27me3 modification between parents could result in allelic bias of H3K27me3 in hybrids. Furthermore, we found that H3K27me3 variation between Col and C24 was negatively correlated with gene expression differences between two accessions, especially with those arising from the cis-effect. Importantly, mutation of CLF, an Arabidopsis methyltransferase for H3K27, altered gene expression patterns between the parents. Together, these data provide insights into natural variation of histone modifications and their association with gene expression differences between Arabidopsis ecotypes.
- Subjects :
- 0301 basic medicine
Arabidopsis
macromolecular substances
Plant Science
medicine.disease_cause
Biochemistry
Methylation
General Biochemistry, Genetics and Molecular Biology
Transcriptome
Histones
03 medical and health sciences
Gene Expression Regulation, Plant
Genetic variation
Gene expression
Botany
medicine
Allele
Alleles
Crosses, Genetic
Genetics
Ecotype
Homeodomain Proteins
Mutation
biology
Arabidopsis Proteins
Lysine
Genetic Variation
biology.organism_classification
030104 developmental biology
Histone
biology.protein
Hybridization, Genetic
Genome, Plant
Subjects
Details
- ISSN :
- 17447909
- Volume :
- 58
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Journal of integrative plant biology
- Accession number :
- edsair.doi.dedup.....0d6e90526887aaaba93ad91299757bca