Back to Search
Start Over
Incidence of pain complaints in oropharyngeal squamous cell carcinoma
- Source :
- Oral surgery, oral medicine, oral pathology and oral radiology. 132(6)
- Publication Year :
- 2020
-
Abstract
- Objective The purpose of this study was to determine the prevalence of throat pain and otalgia as presenting symptoms in patients with oropharyngeal squamous cell carcinoma (OPSCC) stratified by the cancer being their first or recurrent/second primary head and neck cancer (fHNC or rsHNC). Study Design A retrospective analysis of patients operated on for OPSCC was performed. The primary predictor variable was HNC instance (fHNC/rsHNC) with outcome variables of throat pain and/or otalgia. Chi-square analysis was performed to test for significant associations between HNC instance and pain variables. Unadjusted odds ratios were calculated. Results Eighty-nine patients met the inclusion criteria. Patients with OPSCC as an rsHNC had 4.67 times higher odds of throat pain (95% confidence interval [CI], 1.45-15.06) than those with OPSCC as an fHNC and had 20.22 times higher odds of simultaneous throat pain and otalgia (95% CI, 4.76-85.97) than those presenting with an fHNC. Current smoking status and human papillomavirus (HPV)-negative disease were also significantly predictive of rsHNC. HPV-negative disease was also predictive of pain. Conclusions In addition to the known associations of smoking and HPV status on recurrence and pain, there is a statistically significant association between cancer instance and pain in patients presenting with newly diagnosed, operable OPSCC.
- Subjects :
- medicine.medical_specialty
Pain
Disease
Pathology and Forensic Medicine
Odds
03 medical and health sciences
0302 clinical medicine
Throat
Internal medicine
medicine
Humans
Radiology, Nuclear Medicine and imaging
Dentistry (miscellaneous)
Papillomaviridae
Retrospective Studies
business.industry
Squamous Cell Carcinoma of Head and Neck
Incidence (epidemiology)
Incidence
Head and neck cancer
Papillomavirus Infections
Cancer
030206 dentistry
Odds ratio
medicine.disease
Confidence interval
Oropharyngeal Neoplasms
medicine.anatomical_structure
Head and Neck Neoplasms
030220 oncology & carcinogenesis
Carcinoma, Squamous Cell
Surgery
Oral Surgery
Neoplasm Recurrence, Local
business
Subjects
Details
- ISSN :
- 22124411
- Volume :
- 132
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- Oral surgery, oral medicine, oral pathology and oral radiology
- Accession number :
- edsair.doi.dedup.....0d51dedab05892386e35a60d35ab6823