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Similar in vitro response of rat brain nerve terminals, colon preparations and COLO 205 cells to smoke particulate matter from different types of wood
- Source :
- NeuroToxicology. 93:244-256
- Publication Year :
- 2022
- Publisher :
- Elsevier BV, 2022.
-
Abstract
- Major source of carbon-containing air born particular matter that significantly pollutes environment and provokes development of neuropathology is forest fires and wood combustion. Here, water-suspended smoke particulate matter preparations (SPs) were synthesized from birch, pine, poplar wood, and also birch bark and pine needles. Taking into account importance of the gut-brain communication system, SP properties were compared regarding their capability to modulate functioning of nerve terminals and gut cells/preparations. In cortex nerve terminals, poplar wood SP was more effective in decreasing uptake and increasing the extracellular levels of excitatory and inhibitory neurotransmitters L-[
Details
- ISSN :
- 0161813X
- Volume :
- 93
- Database :
- OpenAIRE
- Journal :
- NeuroToxicology
- Accession number :
- edsair.doi.dedup.....0d3043e3aec4cc55b5f9826532e9e371