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Celiac disease screening in patients with scleroderma
- Source :
- Arquivos de Gastroenterologia, Volume: 48, Issue: 2, Pages: 163-164, Published: JUN 2011, Arquivos de Gastroenterologia, Vol 48, Iss 2, Pp 163-164 (2011)
- Publication Year :
- 2011
- Publisher :
- FapUNIFESP (SciELO), 2011.
-
Abstract
- Both celiac disease and scleroderma have autoimmune etiology and affect the bowel causing diarrhea. As an association of autoimmune disease in a single individual is not rare, it is important to know if a patient with scleroderma may also have celiac disease. To analyze this we studied 105 scleroderma patients and 97 volunteers for IgA-EmA by indirect immunofluorescence assay. We could not find a higher prevalence of this autoantibody in scleroderma patients. The authors conclude that there is no need to screen scleroderma patients with diarrhea for celiac disease unless there is a clear clinical indication for this. Tanto a esclerodermia como a doença celíaca são doenças de autoimunidade que causam diarreia. Como o agrupamento de doenças autoimunes em único indivíduo não é raro, é importante saber se um individuo com esclerodermia tem maiores chances de ter ou não doença celíaca. Para isso, estudaram-se 105 pacientes com esclerodermia e 97 controles saudáveis para o anticorpo EmA IgA. Não foi possível detectar presença aumentada de EmA IgA em pacientes com esclerodermia. Conclui-se que não existe necessidade de busca ativa de doença celíaca em pacientes com esclerodermia e diarreia, a menos que existam evidências clínicas claras da doença.
- Subjects :
- Adult
Male
medicine.medical_specialty
Escleroderma, sistêmico
Disease
Scleroderma
Doença celíaca
Disease Screening
medicine
Humans
Celiac disease
lcsh:RC799-869
Fluorescent Antibody Technique, Indirect
skin and connective tissue diseases
Autoantibodies
Autoimmune disease
Scleroderma, Systemic
Transglutaminases
integumentary system
business.industry
Scleroderma, systemic
Gastroenterology
Case-control study
Autoantibody
medicine.disease
Dermatology
digestive system diseases
Immunoglobulin A
Celiac Disease
stomatognathic diseases
Diarrhea
Case-Control Studies
Immunology
Etiology
lcsh:Diseases of the digestive system. Gastroenterology
Female
medicine.symptom
business
Subjects
Details
- ISSN :
- 00042803
- Volume :
- 48
- Database :
- OpenAIRE
- Journal :
- Arquivos de Gastroenterologia
- Accession number :
- edsair.doi.dedup.....0d1b25d73fcd8db1628bf1de0ddf76ee
- Full Text :
- https://doi.org/10.1590/s0004-28032011000200014