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Oral Paracoccidioidomycosis affecting women: A systematic review
- Source :
- Mycoses. 64:108-122
- Publication Year :
- 2020
- Publisher :
- Wiley, 2020.
-
Abstract
- Paracoccidioidomycosis (PCM) is an infection caused by fungi of the genus Paracoccidioides and is marked by a strong predilection for men; nevertheless, some women have had developed PCM and have presented oral involvement by the disease. OBJECTIVES To review all published cases until August 2020 of oral PCM in women, with emphasis on the presence of systemic changes, deleterious habits (tobacco and alcohol) and oral manifestation features through a systematic review. METHODS Observational studies (both prospective and retrospective) and case reports indexed in the Embase, PubMed, Scopus, Web of Science and LIVIVO databases were selected by two reviewers in a two-phase process following the pre-established PICOS criteria. RESULTS Twenty-five studies met the eligibility criteria and were selected for qualitative synthesis, of which 72 participants were enrolled. Brazilian White women between 40 and 50 years were the most affected and social history revealed them to be housewives or rural workers. Fifteen women (33.3% of the informed cases) presented any systemic change at the time of PCM diagnosis, namely pregnancy, HIV infection and/or depression. Moriform stomatitis was predominant and affected preferentially the gingivae and alveolar processes in the form of a single painful lesion. Most patients were treated with sulfamethoxazole + trimethoprim or itraconazole. CONCLUSIONS Oral PCM in women is rare; some cases showed systemic changes at the time of PCM diagnosis, namely HIV infection, pregnancy and depression. New studies should be conducted to elucidate the influence of systemic alterations on the development of oral PCM in women.
- Subjects :
- Adult
0301 basic medicine
medicine.medical_specialty
Databases, Factual
Itraconazole
030106 microbiology
HIV Infections
Dermatology
Disease
030207 dermatology & venereal diseases
03 medical and health sciences
0302 clinical medicine
Pregnancy
Internal medicine
Trimethoprim, Sulfamethoxazole Drug Combination
medicine
Humans
skin and connective tissue diseases
Stomatitis
Depression (differential diagnoses)
Coinfection
business.industry
Paracoccidioidomycosis
Sulfamethoxazole
Paracoccidioides
General Medicine
Middle Aged
medicine.disease
Trimethoprim
Infectious Diseases
Female
business
Brazil
medicine.drug
Subjects
Details
- ISSN :
- 14390507 and 09337407
- Volume :
- 64
- Database :
- OpenAIRE
- Journal :
- Mycoses
- Accession number :
- edsair.doi.dedup.....0d19aeed8a1fb9870f8d75cc7bd48fb8