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Developmental and pharmacological features of mouse emotional piloerection
- Source :
- Experimental animals. 48(3)
- Publication Year :
- 1999
-
Abstract
- We demonstrated emotional piloerection in mice given conditioned fear stress by means of a pass-through apparatus. The emotional piloerection was first assessed in mice of different ages. The results showed that the piloerection changed with age. Pharmacological studies showed that the piloerection was inhibited by an alpha 1-adrenoceptor antagonist prazosin, but, surprisingly, was not inhibited by anxiolytic diazepam. These findings strongly suggest that the neuronal system of piloerection is different from that of freezing behavior, and that the neuronal system of piloerection develops with age.
- Subjects :
- Male
medicine.medical_specialty
Aging
medicine.drug_class
Conditioning, Classical
Alpha (ethology)
Anxiolytic
Developmental change
General Biochemistry, Genetics and Molecular Biology
Piloerection
Mice
Internal medicine
medicine
Prazosin
Animals
Psychiatry
Adrenergic alpha-Antagonists
Diazepam
General Veterinary
Behavior, Animal
business.industry
Antagonist
Yohimbine
General Medicine
Propranolol
Electric Stimulation
Freezing behavior
Endocrinology
Animal Science and Zoology
business
Stress, Psychological
medicine.drug
Subjects
Details
- ISSN :
- 13411357
- Volume :
- 48
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Experimental animals
- Accession number :
- edsair.doi.dedup.....0d19a6f1178b969c212a571ce661f484