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Antiviral activity of cathelicidin 5, a peptide from Alligator sinensis, against WSSV in caridean shrimp Exopalaemon modestus
- Source :
- Fish & Shellfish Immunology. 93:82-89
- Publication Year :
- 2019
- Publisher :
- Elsevier BV, 2019.
-
Abstract
- White spot disease caused by white spot syndrome virus (WSSV) is responsible for harming shrimp aquaculture industry and results in a pandemic throughout the world. Cathelicidin 5 treatment enhanced immune parameters including antioxidant enzyme activity and immune-related genes expression in shrimp Exopalaemon modestus. Shrimp treated with cathelicidin 5 and inoculated with white spot syndrome virus (WSSV) exhibited a significantly lower mortality rate and lower viral VP28 amplification and expression than control. This study addresses the role of cathelicidin 5 in immune stimulatory and antiviral activities that could protect E. modestus from WSSV infection.
- Subjects :
- 0301 basic medicine
medicine.medical_treatment
Alligator
White spot syndrome
Reptilian Proteins
Aquatic Science
Biology
Antiviral Agents
Virus
Microbiology
Cathelicidin
Random Allocation
03 medical and health sciences
White spot syndrome virus 1
Immune system
Adjuvants, Immunologic
Cathelicidins
biology.animal
medicine
Animals
Environmental Chemistry
Gene
Alligators and Crocodiles
Dose-Response Relationship, Drug
04 agricultural and veterinary sciences
General Medicine
biology.organism_classification
Enzyme assay
Shrimp
030104 developmental biology
040102 fisheries
biology.protein
0401 agriculture, forestry, and fisheries
lipids (amino acids, peptides, and proteins)
Palaemonidae
Subjects
Details
- ISSN :
- 10504648
- Volume :
- 93
- Database :
- OpenAIRE
- Journal :
- Fish & Shellfish Immunology
- Accession number :
- edsair.doi.dedup.....0cfefe8e7525abb10c30a613612891e8