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Isosteric Mercurial Diuretics

Authors :
William Jones
Donald B. Meyers
John W. Martin
Source :
Journal of Pharmaceutical Sciences. 50:487-490
Publication Year :
1961
Publisher :
Elsevier BV, 1961.

Abstract

Four isosteric mercurial diuretics were synthesized and studied to ascertain the difference between the amide and ester grouping on diuretic activity. A method of synthesis and evidence for an anhydro zwitterion type of structure are presented.

Details

ISSN :
00223549
Volume :
50
Database :
OpenAIRE
Journal :
Journal of Pharmaceutical Sciences
Accession number :
edsair.doi.dedup.....0cceb0200e7ebe11c5d7d6173c0fd798
Full Text :
https://doi.org/10.1002/jps.2600500609