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Clinical Features and Survival Outcomes in Patients with Multiple Myeloma: Analysis of Web-Based Data from the Korean Myeloma Registry
- Source :
- Acta Haematologica. 122:200-210
- Publication Year :
- 2009
- Publisher :
- S. Karger AG, 2009.
-
Abstract
- Aim: The Korean Multiple Myeloma Working Party performed a nationwide registration of multiple myeloma patients via a web-based data bank system. Methods: We retrospectively analyzed registered data from 3,209 patients since 1999. Results: The median overall survival (OS) was 50.13 months (95% confidence interval: 46.20–54.06 months). Patients ≤40 years demonstrated a longer OS than patients >65 years of age (median OS 71.13 vs. 36.73 months, p < 0.001). Patients who received novel agents at any time during their treatments showed a longer OS than patients who did not (median OS 42.23 vs. 55.50 months, p < 0.001). Response to treatment was associated with OS, with tandem autologous stem cell transplantation (SCT) producing longer OS than single autologous SCT. Conclusions: We demonstrated associations between survival outcomes and treatment modalities as well as baseline disease characteristics in a registry of multiple myeloma patients using a web-based data analysis.
- Subjects :
- Adult
Male
Oncology
medicine.medical_specialty
MEDLINE
Kaplan-Meier Estimate
Transplantation, Autologous
Young Adult
immune system diseases
hemic and lymphatic diseases
Internal medicine
Republic of Korea
Humans
Transplantation, Homologous
Medicine
Web application
In patient
Registries
Young adult
Multiple myeloma
Aged
Aged, 80 and over
Chromosome Aberrations
Internet
business.industry
Hematology
General Medicine
Middle Aged
Prognosis
medicine.disease
Surgery
Transplantation
Female
Multiple Myeloma
business
Stem Cell Transplantation
Subjects
Details
- ISSN :
- 14219662 and 00015792
- Volume :
- 122
- Database :
- OpenAIRE
- Journal :
- Acta Haematologica
- Accession number :
- edsair.doi.dedup.....0c747287c957bf49f7a42c6a4b150ba3
- Full Text :
- https://doi.org/10.1159/000253027