Functional and Quality Requirements for Susceptibility Genetic Testing in Cancer Care: The Case of BRCA1/2 Testing in Jordan

Breast cancer is the most common cancer in Jordan. Mutations in BReast CAncer susceptibility gene 1 and BReast CAncer susceptibility gene 2 (BRCA1/2 genes) greatly increase the lifetime risk of developing breast and/or ovarian cancer in women. The aim of this paper is to identify functional and non-functional requirements for BRCA 1/2 testing, as a corner stone for establishing BRCA 1/2 testing services in the country and as a case example for other susceptibility genetic testing for cancer. During two sessions, the authors outlined the functional and non-functional requirements for BRCA1/2 testing, as types of categories of requirements, using the Sommerville approach. Six functional requirements were identified. Non-functional requirements were divided to: 1. Product related 2. Process related and 3. Externally related (Interoperability and Legal, Social, Ethical and Professional (LSEP) Implications). The authors will continue to build on their work in order to produce a full model for BRCA1/2 testing to provide the most comprehensive and advanced cancer care for patients and facilitate future development of innovate measures in the battle against cancer.