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Levodopa-responsive retrocollis on the background of choreic dyskinesia

Authors :
Shinichiro Inatomi
Yasuhiko Sawada
Hitoshi Yoshiji
Kazuma Sugie
Naotaka Shimozato
Hiroshi Kataoka
Source :
The International journal of neuroscience. 130(5)
Publication Year :
2019

Abstract

Purpose/aim: Retrocollis can substantially disturb the daily living of individuals with Parkinson's disease (PD). Clinician often encounter the difficulty in managing the retrocollis. Materials and Methods: We describe a patient with PD who presented with choreic dyskinesia and levodopa-responsive retrocollis. Results: The patient had dyskinesia and the off periods, and received levodopa (700 mg, 14 times/day). The patient received levodopa-carbidopa intestinal gel (LCIG) treatment. After several months, the patient complained of difficulty in swallowing and speech due to severe retrocollis. Thirty minutes following a fast levodopa infusion of LCIG, the retrocollis improved. As a result, a frontal view was obtained, and her talking abilities showed improvement. Conclusions: Severe retrocollis can be superimposed on choreic dyskinesia, and it was likely to increase during the off periods. Duodenal levodopa infusion may reduce the severity of retrocollis.

Details

ISSN :
15635279
Volume :
130
Issue :
5
Database :
OpenAIRE
Journal :
The International journal of neuroscience
Accession number :
edsair.doi.dedup.....0c4b1ecb04b796764419058a78292501