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The challenge of West Nile virus in Europe: knowledge gaps and research priorities
- Source :
- Scopus-Elsevier, Digital.CSIC. Repositorio Institucional del CSIC, instname, Eurosurveillance, Eurosurveillance, European Centre for Disease Prevention and Control, 2015, 20 (20), ⟨10.2807/1560-7917.ES2015.20.20.21135⟩, Europe PubMed Central, Eurosurveillance, 20(20), 28-42. European Centre for Disease Prevention and Control (ECDC), Repositorio de Resultados de Investigación del INIA, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria INIA, Eurosurveillance, 2015, 20 (20), ⟨10.2807/1560-7917.ES2015.20.20.21135⟩, INIA: Repositorio de Resultados de Investigación del INIA, EUROSURVEILLANCE
- Publication Year :
- 2015
- Publisher :
- European Centre for Disease Control and Prevention (ECDC), 2015.
-
Abstract
- West Nile virus (WNV) is continuously spreading across Europe, and other continents, i.e. North and South America and many other regions of the world. Despite the overall sporadic nature of outbreaks with cases of West Nile neuroinvasive disease (WNND) in Europe, the spillover events have increased and the virus has been introduced into new areas. The high genetic diversity of the virus, with remarkable phenotypic variation, and its endemic circulation in several countries, require an intensification of the integrated and multidisciplinary research efforts built under the 7th Framework Programme of the European Union (FP7). It is important to better clarify several aspects of WNV circulation in Europe, including its ecology, genomic diversity, pathogenicity, transmissibility, diagnosis and control options, under different environmental and socio-economic scenarios. Identifying WNV endemic as well as infection-free areas is becoming a need for the development of human vaccines and therapeutics and the application of blood and organs safety regulations. This review, produced as a joint initiative among European experts and based on analysis of 118 scientific papers published between 2004 and 2014, provides the state of knowledge on WNV and highlights the existing knowledge and research gaps that need to be addressed with high priority in Europe and neighbouring countries.
- Subjects :
- Health Knowledge, Attitudes, Practice
Veterinary medicine
Economic growth
WNV STRAINS
Epidemiology
viruses
MESH: Health Knowledge, Attitudes, Practice
medicine.disease_cause
Disease Outbreaks
EXPERIMENTAL-INFECTION
ENVELOPE PROTEIN
Neuroinvasive disease
Medicine and Health Sciences
MESH: Genetic Variation
MESH: Disease Outbreaks
MESH: Phylogeny
Phylogeny
media_common
EARLY WARNING SYSTEM
biology
SUBSTITUTION
AMINO-ACID
3. Good health
Europe
MESH: Research
Geography
Population Surveillance
[SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology
West Nile virus
SPARROWS PASSER-DOMESTICUS
media_common.quotation_subject
Ecology (disciplines)
MESH: Population Surveillance
SDG 3 - Good Health and Well-being
Virology
medicine
Humans
media_common.cataloged_instance
Veterinary Sciences
European union
TIME RT-PCR
Settore VET/06 - PARASSITOLOGIA E MALATTIE PARASSITARIE DEGLI ANIMALI
MESH: West Nile virus
MESH: West Nile Fever
MESH: Humans
Research
LINEAGE 1 STRAIN
Public Health, Environmental and Occupational Health
Genetic Variation
Outbreak
biology.organism_classification
USUTU VIRUS
Early warning system
MESH: Europe
CULEX-PIPIENS MOSQUITOS
Usutu virus
West Nile Fever
Diversity (politics)
Subjects
Details
- ISSN :
- 15607917 and 1025496X
- Volume :
- 20
- Database :
- OpenAIRE
- Journal :
- Eurosurveillance
- Accession number :
- edsair.doi.dedup.....0c3618bcec3000cbd04013eb280ba66f